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NLRP3炎症小体与抑郁症的相关性研究进展
周鑫鑫胡建
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摘要:
抑郁症严重影响人们的身心健康,其发病机制涉及神经递质紊乱、内分泌、炎症、氧化应 激等多方面。近几年来,有关抑郁症在炎症免疫系统方面的研究日益增多,NLRP3 炎症小体在免疫系 统功能中起重要的作用。现针对NLRP3 炎症小体在抑郁症发病中的机制作简要综述,为抑郁症的诊断 和治疗提供新的参考。
关键词:  抑郁症  NLRP3炎症小体  发病机制  综述
DOI:10.3969/j.issn.1009-6574.2018.11.013
基金项目:
Research progress on the relationship between NLRP3 inflammatory body and depression
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Abstract:
Depression seriously affects people's physical and mental health, and its pathogenesis involves neurotransmitter disorder, endocrine, inflammation, oxidative stress and so on. In recent years, the study of depression in the inflammatory immune system has been increasing. NLRP3 inflammatory body plays an important role in the immune system function. This article reviews the mechanism of NLRP3 inflammatory body in the pathogenesis of depression, and provides a new reference for the diagnosis and treatment of depression.
Key words:  Depression  NLRP3 inflammatory body  Pathogenesis  Review

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