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急性单发性脑梗死与继发性不宁腿综合征的相关性
刘艳婷张美云牛宝丰
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摘要:
目的 分析在急性单发性脑梗死(ASCI)患者中,梗死部位与继发性不宁腿综合征(SRLS) 的关系。方法 回顾性连续收集ASCI 患者556 例,收集人口统计学特征、化验结果、影像资料、并存疾 病、ASCI 临床特征等资料,并分为SRLS 组和非SRLS 组。对两组进行比较,采用单因素分析探讨ASCI 患者SRLS 的相关因素,多因素分析探讨ASCI 患者SRLS 的独立相关因素。结果 纳入的556 例ASCI 患者中,26 例(4.68%)并发SRLS。单因素分析显示,尿酸与SRLS 发病相关(P< 0.05),丘脑及脑桥部位 ASCI 患者SRLS发病率较高,纳入多因素分析显示,ASCI 位于丘脑(OR=5.81,P< 0.05)和脑桥(OR=2.65, P< 0.05)是并发SRLS的独立相关因素。结论 在ASCI患者中,梗死部位与SRLS 发病相关,丘脑和脑 桥部位ASCI 可能是SRLS的独立预测因素。
关键词:  脑梗死  不宁腿综合征  丘脑  脑桥
DOI:10.3969/j.issn.1009-6574.2019.04.016
基金项目:
Relationship of acute single cerebral infarction and secondary restless legs syndrome
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Abstract:
Objectives To analyze the relationship between the location of acute single cerebral infarction( ASCI) and secondary restless leg syndrome( SRLS). Methods The data of 556 continuous patients with ASCI were collected retrospectively, including demographic characteristics, laboratory results, imaging data, coexisting diseases, clinical characteristics of ASCI. All the patients were divided into SRLS group and non-SRLS group. Comparing between the two groups, univariate analysis was used to explore the related factors of SRLS in patients with ASCI, and multivariate analysis was used to explore the independent related factors of SRLS in patients with ASCI. Results Of the 556 ASCI patients included, 26( 4.68%) suffered SRLS. Univariate analysis revealed uric acid was associated with the morbidity of SRLS( P<0.05), and the incidence of SRLS was higher in thalamic and pons ASCI patients. Multivariate analysis revealed that ASCI occurring in the location of thalamus( OR=5.81,P< 0.05) and pons( OR=2.65, P< 0.05) are independent predictors for SRLS. Conclusions In patients with ASCI, the location of infarction is associated with the morbidity of SRLS, and ASCI occurring in the thalamus and pons may be independent predictors for SRLS.
Key words:  Cerebral infarction  Restless leg syndrome  Thalamus  Pons

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