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细胞焦亡与动脉粥样硬化
宋辉辉孙瑞红
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摘要:
动脉粥样硬化是缺血性血管疾病的重要病因之一,炎症和细胞死亡在其发生发展过程中 发挥重要作用。而细胞焦亡是一种促炎性细胞程序性死亡。最近的研究表明,内皮细胞、巨噬细胞及 平滑肌细胞的焦亡加速了动脉粥样硬化进程。因此更好地了解细胞焦亡可能为预防和治疗动脉粥样硬 化相关疾病提供新方法。现就细胞焦亡与动脉粥样硬化的关系作一综述。
关键词:  动脉粥样硬化  细胞焦亡  综述
DOI:10.3969/j.issn.1009-6574.2019.04.022
基金项目:黑龙江省科研计划项目(201602)
Pyroptosis and atherosclerosis
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Abstract:
Atherosclerosis is one of the most essential causes of ischemic vascular disease, while inflammation and cell death play an important role during its development. Pyroptosis is a programmed proinflammatory cell death proess. Recent studies have shown that the pyroptosis of endothelial cells, macrophages and smooth muscle cells accelerates the progress of atherosclerosis. Therefore,It may provide us a new method for the prevention and treatment of atherosclerosis-related diseasesa to have a better understanding of pyroptosis. This article aims at reviewing the relationship between pyroptosis and atherosclerosis.
Key words:  Atherosclerosis  Pyroptosis  Review

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