引用本文:[点击复制]
[点击复制]
【打印本页】 【在线阅读全文】【下载PDF全文】 查看/发表评论下载PDF阅读器关闭

←前一篇|后一篇→

过刊浏览    高级检索

本文已被:浏览 629次   下载 797  
迷走神经刺激术治疗药物难治性癫痫的疗效及安全性
陈富勇魏明怡孟祥红付萌萌冯刚李瑞麒陶蔚
0
()
摘要:
目的 探讨迷走神经刺激术治疗药物难治性癫痫的疗效及安全性。方法 回顾分析2016年 8 月至2019 年11 月收治的17 例行迷走神经刺激术的药物难治性癫痫患者的临床资料,对其进行随访, 观察疗效和并发症。结果 17 例患者刺激时间6~29 个月,疗效判定采用McHugh 分级,6 例为McHugh Ⅰ A 级,7 例为McHugh Ⅱ A 级, 2 例为McHugh Ⅱ B 级,1 例为McHugh Ⅲ A 级,1 例为McHugh Ⅴ级。对 随访1 年以内及1 年以上进行分组疗效对比,差异无统计学意义。术后4 例患者有一过性声音嘶哑和开 机后咳嗽,无感染发生,无严重并发症发生。结论 对于药物难治性癫痫患者,尤其是对于无法行切除 性手术患者,迷走神经刺激术是一个安全有效的选择。
关键词:  癫痫  迷走神经刺激  疗效  并发症
DOI:10.3969/j.issn.1009-6574.2019.05.008
基金项目:深圳市科创委基础研究(学科布局)项目(JCYJ20160428164548896,JCYJ20170412111316339); 深圳大学总医院科技人才助推计划(SUGH-301)
Efficacy and safety of vagus nerve stimulation for the drugs-refractory epilepsy
()
Abstract:
Objectives To investigate the efficacy and safety of vagus nerve stimulation( VNS) in the treatment of refractory epilepsy. Methods We retrospectively analyzed the clinical data of 17 patients with refractory epilepsy who underwent vagal nerve stimulation from August 2016 to November 2018, including curative effects and complications. Results All the patients were followed up for 6-29 months. The efficacy was evaluated according to McHugh classification, 6 patients were McHugh Class Ⅰ A , and 7 patients were McHugh Class Ⅱ A, 2 patients were McHugh Class Ⅱ B, 1 patient was McHugh Class Ⅲ A, 1 patient was McHugh Class Ⅴ . There was no statistically significant difference in the efficacy between the group within one year of follow-up and the one of more than one year. No severe side effect or surgical complication was observed, except for 4 patients with hoarse voice and cough after having VNS machine on. Conclusions Vagal nerve stimulation is a safe and effective option to the patients with refractory epilepsy, especially for the patients who were also not belong to the candidate for resection surgery.
Key words:  Epilepsy  Vagus nerve stimulation  Curative effects  Complications

用微信扫一扫

用微信扫一扫