| 摘要: |
| 精神分裂症暴力和攻击行为已经成为影响社会和公共卫生问题之一，研究显示精神分裂
症患者的暴力犯罪率高于一般人群的 4～7 倍。遗传、神经生化和代谢等生物学因素在精神分裂症患者
的暴力和攻击行为中起到重要作用。因此，针对精神分裂症暴力和攻击行为的生物学机制研究具有重
要现实意义。现针对精神分裂症暴力和攻击行为的生物学研究进展进行综述。 |
| 关键词: 精神分裂症 暴力 攻击性行为 基因 神经递质 炎症因子 |
| DOI：10.3969/j.issn.1009-6574.2020.12.001 |
|
| 基金项目:国家自然科学基金青年基金资助项目（81801881）；中央级科研院所科研专项资金资助项
目（GY2020G-3）；上海市“科技创新行动计划”社会发展科技攻关项目（20dz1200300）；国家重点研发计
划项目（2016YFC0800701）；合肥市第四人民医院院内科研项目（HFSY2020YB21） |
|
| Biological research progress on violence and aggressive behavior in schizophrenia |
| Ju Peijun， Zhu Cuizhen |
| () |
| Abstract: |
| Violent and aggressive behaviors in schizophrenia has become one of the problems affecting
society and public health. Studies have shown that the violent crime rate of schizophrenia patients is 4-7 times
higher than that of the general population. Biological factors such as genetics， neurobiochemistry and metabolism
play important roles in the violent and aggressive behaviors of patients with schizophrenia. Therefore， it is of
great significance to study the biological mechanism of violence and aggressive behavior in schizophrenia. This
review focuses on the biological research progress of violence and aggressive behavior in schizophrenia. |
| Key words: Schizophrenia Violence Aggressive behavior Genes Neurotransmitters Inflammatory factors |
