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有自杀企图史的抑郁症住院患者临床特征 研究
邢笑萌赵茜史晓宁张玲
0
()
摘要:
目的 研究有自杀企图史的抑郁症住院患者临床特点及相关危险因素。方法 回顾性 连续纳入 2013 年 12 月至 2016 年 11 月于首都医科大学附属北京安定医院抑郁症治疗中心住院的 472 例 抑郁症重度发作患者,根据有无自杀企图史将所有患者分为有自杀企图史组与无自杀企图史组。对有 自杀企图史和无自杀企图史患者的人口学资料、疾病特征、治疗药物、实验室检查指标等进行单因素和 多因素分析,对有自杀企图史的影响因素进行多元 Logistic 回归分析。结果 有自杀企图史组 120 例, 无自杀企图史组 352 例。与无自杀企图史组比较,有自杀企图史组女性多[68.33%(82/120)比 57.39% (202/352),χ2 =4.48,P< 0.05]、发病年龄早[34.00(24.25,44.00)岁比 38.00(27.00,49.00)岁;Z=-2.01, P< 0.05]、病程长[6.50(1.00,15.00)年比 3.00(0.58,10.00)年;Z=-3.07,P< 0.01]、发作次数多[2.00 (2.00,3.75)次比 2.00(1.00,3.00)次;Z=-3.01,P< 0.01)]。多元 Logistic 回归分析结果显示,女性(OR=1.64, 95%CI:1.05~2.56,P< 0.05)和病程长(OR=1.04,95%CI:1.01~1.07,P< 0.05)是患者有自杀企图史的 危险因素。结论 有自杀企图史的抑郁症患者有其相应的临床特点,如女性、病程长、发作次数多等, 对相关因素进行分析研究,有助于临床中对自杀风险进行预防及针对性治疗。
关键词:  抑郁症  自杀企图  临床特征
DOI:10.3969/j.issn.1009-6574.2020.03.003
基金项目:北京市科学技术委员会北京市脑计划抑郁症队列项目 (Z181100001518005)
Clinical characteristics of depression inpatients with suicide attempt history
Xing Xiaomeng, Zhao Qian, Shi Xiaoning, Zhang Ling
()
Abstract:
Objective To explore the clinical characteristics and related risk factors of depression inpatients with a history of suicide attempts. Methods A retrospective analysis was performed on clinical data of all 472 patients with depressive disorder who were admitted to Depression Treatment Center in Beijing Anding Hospital between December 2013 and November 2016. According to the history of suicide attempt, all patients were divided into two groups: the group with history of suicide attempt and the group without history of suicide attempt. The demographic data, disease characteristics, therapeutic drugs and laboratory parameters of patients with and without a history of suicide attempts were compared. The relevant data were analyzed by multivariate Logistic regression. Results There were 120 cases in the group with a history of suicide attempts, 352 cases in the group without a history of suicide attempts. Compared with the non-suicide attempt group, the characteristics of suicide attempt group were more in female [68.33%(82/120) vs. 57.39%(202/352), χ2 =4.48,P < 0.05], earlier onset age [34.00(24.25,44.00) vs. 38.00(27.00,49.00),Z=-2.01,P < 0.05], longer duration [6.50 (1.00,15.00) vs. 3.00(0.58,10.00), Z=-3.07,P< 0.01], and more episodes [2.00(2.00,3.75) vs. 2.00(1.00, 3.00),Z=-3.01,P < 0.01]. Multiple regression analysis showed that female (OR=1.64, 95%CI:1.05-2.56, P< 0.05) and long duration (OR=1.04, 95%CI: 1.01-1.07,P< 0.05) were the risk factors for suicide attempts. Conclusions Female, long duration of disease and multiple episodes are the risk factors of suicide attempts in depression patients. Further researches are needed for the prevention and intervention of suicidal attempts in patients with depression
Key words:  Depression  Suicidal attempt  Clinical characteristics

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