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胰岛素样生长因子-1与癫痫相关性的研究进展
陈丹崔鑫张蓓李亚军
0
()
摘要:
癫痫是神经系统常见疾病之一,癫痫发作可导致脑损伤已被动物实验和临床观察证实。 胰岛素样生长因子-1(IGF-1)是神经营养保护因子,在中枢神经系统的生长、发育、分化、损伤后修复中 起到重要作用,然而它在癫痫发作中所起的作用存在争议,现回顾目前IGF-1 与癫痫相关研究,对IGF-1 与癫痫关系进行系统综述。
关键词:  癫痫  胰岛素样生长因子1  脑损伤  综述
DOI:10.3969/j.issn.1009-6574.2020.07.012
基金项目:
Research progress on the relationship between Insulin-like growth factor-1 and epilepsy
Chen Dan, Cui Xin, Zhang Bei, Li Yajun
()
Abstract:
Epilepsy is one of the common diseases of the nervous system. Brain injuries caused by seizures has been confirmed by animal experiments and clinical observations. Insulin-like growth factor-1(IGF-1) is a neurotrophic protective factor, which plays an important role in the growth, development, differentiation and repair of the central nervous system after injury. However, its role in seizures is controversial. This paper reviews the current research on IGF-1 and epilepsy, and discusses the relationship between IGF-1 and epilepsy based on a large number of literatures.
Key words:  Epilepsy  Insulin-like growth factor-1  Brain injuries  Review

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