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急性脑梗死后继发不安腿综合征20例分析 及文献复习
杜艺彤田泽龙许晓娇脱厚珍
0
()
摘要:
目的 总结急性脑梗死后继发不安腿综合征(RLS)的临床、影像学特征。方法 回顾性 分析2012 年1 月至2019 年1 月北京友谊医院诊治的20 例急性脑梗死后继发RLS 患者的临床表现、头 颅磁共振(MRI)影像及治疗方案,总结其临床特征。结果 20 例急性脑梗死后继发RLS 患者的年龄为 (62.65±9.40)岁;其中男性12 例,女性8 例,男女比例3∶2。梗死部位位于脑桥、放射冠、半卵圆中心、 丘脑、壳核及枕叶。20 例患者均出现梗死病灶对侧的肢体瘫痪,12 例患者出现梗死病灶对侧的肢体感 觉障碍。12 例患者梗死灶对侧出现RLS 症状,8 例患者双侧肢体均有发病。其中15 例患者接受多巴胺 能药物治疗,治疗后RLS临床症状均显著改善。结论 急性脑梗死后继发RLS的常见梗死部位为脑桥(多 为脑桥核受累)、半卵圆中心和基底神经节。与原发性RLS相比,急性脑梗死后继发RLS多为单侧发病,可 累及上肢,多巴胺能药物治疗有效。
关键词:  急性脑梗死  不安腿综合征  临床特点
DOI:10.3969/j.issn.1009-6574.2021.06.010
基金项目:
Clinical characteristics and literature review of restless legs syndrome secondary to acute cerebralinfarction
Du Yitong, Tian Zelong, Xu Xiaojiao, Tuo Houzhen
()
Abstract:
Objective To summarize the clinical and imaging features of secondary restless legs syndrome( RLS) after acute cerebral infarction. Methods The clinical manifestations, MRI images and treatment plans of 20 patients with RLS after acute cerebral infarction treated by Beijing Friendship Hospital from January 2012 to January 2019 were analyzed retrospectively, to summarize their clinical features. Results The average age of the 20 patients with secondary RLS after acute cerebral infarction was( 62.65±9.40) years old, including 12 males and 8 females, with a male to female ratio of 3∶2. The infarctions were located in the pons, radial crown, centrum semiovale, thalamus, putamen and occipital lobe. All 20 patients had limb paralysis on the contralateral side of the infarction, and 12 patients had dysesthesia of the limb contralateral to the infarct lesion. RLS occurred in the contralateral side of infarct in 12 patients and in both limbs in 8 patients. Among them, 15 patients were treated with dopaminergic drugs, and the clinical symptoms of RLS were significantly improved after treatment. Conclusions The common infarct sites of secondary RLS after acute cerebral infarction are the pons( mostly parabrachial nucleus involvement), centrum semiovale and basal ganglia. Compared with idiopathic RLS, secondary RLS after acute cerebral infarction is mostly unilateral, which can affect upper limbs, and dopaminergic drugs are effective.
Key words:  Acute cerebral infarction  Restless legs syndrome  Clinical features

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