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精神分裂症现实监控缺陷的研究进展
陈颖徐丽华甘冉飘张天宏王继军
0
()
摘要:
现实监控过程对于维持日常生活的正常运行不可或缺,它能帮助人们识别自身的想法、 感受和想象,并将它们与真实的经历或由他人讲述的事件区分开来。现实监控出现错误时,往往是将 内部生成的事件错误识别为真实的,涉及的范围从混淆真实与想象的经历到精神病性症状(如幻听)的 出现,其程度的不同取决于现实监控的能力。精神分裂症患者的现实监控能力明显受损,通过现实监 控研究可以更好地理解精神分裂症的脑机制和寻找新干预靶点。因此,现对精神分裂症现实监控缺陷 的研究进展进行综述。
关键词:  精神分裂症  现实监控  内侧前额叶皮层  综述
DOI:10.3969/j.issn.1009-6574.2021.06.011
基金项目:国家重点研发计划“重大慢性非传染性疾病防控研究”项目(2016YFC1306800);上海交 通大学“转化医学交叉研究基金”青年B 类项目(ZH2018QNB19);上海市“科技创新行动计划”自然科 学基金面上项目(20ZR1448600)
Research progress on the deficiency of reality monitoring in schizophrenia
Chen Ying, Xu Lihua, Gan Ranpiao, Zhang Tianhong, Wang Jijun
()
Abstract:
The reality monitoring is essential to keeping our daily lives in balance. It can help us identify our thoughts, feelings and imaginations, and distinguish them from real experiences or events told by others. When the reality monitoring errors occur, individual often misidentifies internal generated events as real, ranging from experiences of confusing reality with imagination to psychotic symptoms such as auditory hallucination, the degree of which depends on the reality-monitoring ability. The reality-monitoring ability of patients with schizophrenia is obviously impaired. Research on reality monitoring can help us better understand the brain mechanism of schizophrenia and find new targets for intervention. Therefore, this paper will review the research progress on the deficiency of reality monitoring in schizophrenia.
Key words:  Schizophrenia  Reality monitoring  Media prefrontal cortex  Review

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