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失匹配负波对精神分裂症不同阶段识别作用的研究进展
秦湘琴  侯文鹏  李先宾  王传跃  
0
()
摘要:
精神分裂症及早期精神病的识别严重依赖症状学的主观判断,缺乏可应用于临床的生物 标志。失匹配负波是由大脑对听觉刺激的变化超过特定界值进行自动反应所产生的、在慢性精神分裂 症中具有明确而突出的缺陷,但其相关指标在早期精神病中的研究尚处于早期阶段。现拟梳理听觉失 匹配负波相关指标在识别精神分裂症不同阶段中的应用进展,为进一步地深入研究提供参考。
关键词:  精神分裂症  失匹配负波  综述
DOI:10.3969/j.issn.1009-6574.2022.06.006
基金项目:国家自然科学基金项目(81971287);首都卫生发展科研专项项目(首发 2018-2-2123); 北京市医院管理局扬帆计划临床技术创新项目(XMLX201807)
Research progress of mismatch negativity in the recognition of different stages of schizophrenia
Qin Xiangqin,Hou Wenpeng,Li Xianbin,Wang Chuanyue
()
Abstract:
The identification of schizophrenia and early psychosis depends heavily on the subjective judgment of symptomatology, and there is a lack of biomarkers that can be used in clinic. Mismatch negativity is generated by the brain's automatic response to the change of auditory stimulation beyond a specific threshold, which has a clear and prominent defect in chronic schizophrenia, but the study of its related indicators in early psychosis is still in the early stage. This paper aims to summarize the application progress of related indicators of auditory mismatch negativity in the recognition of different stages of schizophrenia,and provide references for further research.
Key words:  Schizophrenia  Mismatch negativity  Review

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