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住院成年早期双相情感障碍患者自杀相关因素研究
孙丛丛  吴涵  贾立娜  潘伟刚  
0
()
摘要:
目的 探索分析成年早期双相情感障碍住院患者自杀行为的相关因素。方法 选取 2018 年 1— 12 月在首都医科大学附属北京安定医院住院的 521 例成年早期(18~25 岁)双相情感障碍 患者为研究对象,按照是否曾有过自杀,分为自杀组(n=140)与无自杀组(n=381),比较两组患者的 一般资料及疾病亚型。通过二分类 Logistic 回归分析探讨成年早期双相情感障碍患者自杀危险因素。 结果 与无自杀组比较,自杀组女性[70.0%(98/140)比 47.8%(182/381)]、冲动性格者[29.3%(41/140) 比 19.2%(73/381)]、有重大精神创伤史者[14.3%(20/140)比 4.5%(17/381)]占比更高,差异均有统计 学意义(χ2 =20.350、6.141、16.941;P< 0.05)。二分类 Logistic 回归分析显示,女性[OR=0.375,95%CI (0.226~0.564),P< 0.001]、冲动性格[OR=0.603,95%CI(0.377~0.963),P=0.034]、有重大精神创伤史 [OR=0.295,95%CI(0.144~0.604),P=0.001]是成年早期双相情感障碍患者发生自杀的独立危险因素。 结论 女性、性格冲动、有重大精神创伤史的成年早期双相情感障碍患者发生自杀的风险更高。
关键词:  双相情感障碍  自杀  成年早期
DOI:10.3969/j.issn.1009-6574.2022.06.009
基金项目:北京市科学委员会重大专项(D171100007017001)
Study on suicide-related factors of inpatients with bipolar disorder in early adulthood
Sun Congcong,Wu Han,Jia Lina,Pan Weigang
()
Abstract:
Objective To explore and analyze the related factors of suicidal behavior in hospitalized patients with early adult bipolar disorder. Methods A total of 521 inpatients with bipolar disorder in early adulthood (aged between 18 to 25) in Beijing Anding Hospital affiliated to Capital Medical University from January to December 2018 were recruited as the research subjects. They were divided into suicide group (n=140) and no suicide group (n=381) according to whether they had ever committed suicide. The general data and disease subtypes of the two groups were compared. The risk factors related to suicide in early adult patients with bipolar disorder were analyzed by binary Logistic regression analysis. Results Compared with the suicide group, there were more female in the suicide group [70% (98/140) vs 47.8% (182/381), χ2 =20.350, P< 0.01], more impulsive personality [29.3% (41/140) vs 19.2% (73/381), χ2 =6.141, P=0.013], and there were more people with a history of major trauma [14.3% (20/140) vs 4.5% (17/381), χ2 =16.941, P< 0.01]. The differences were statistically significant. Binary Logistic regression analysis showed female [OR=0.375, 95%CI (0.226-0.564)], impulsive personality [OR=0.603, 95%CI (0.377-0.963)], history of major trauma [OR=0.295, 95%CI (0.144-0.604)]were the independent risk factors for suicidal behavior in patients with bipolar disorder in early adulthood (P< 0.05). Conclusions Patients with bipolar disorder in early adulthood who are females, have longer disease course, have impulsive personality, and have a history of major trauma are at higher risk of suicide.
Key words:  Bipolar disorder  Suicide  Early adulthood

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