| 摘要: |
| 阿尔茨海默病（AD）是常见的进行性中枢神经系统退行性疾病，以进行性认知功能下降为
主要临床特征，是导致痴呆的主要原因。遗忘型轻度认知功能障碍（a-MCI）是轻度认知功能障碍（MCI）
的一种亚型。研究表明，a-MCI 大多会进展为 AD，积极干预 a-MCI 是延缓或减少 AD 发生的关键。目前
用于治疗 a-MCI 的药物均缺少大样本的循证医学证据，临床科研工作者越来越关注认知训练在 a-MCI 非
药物治疗领域的研究。认知训练的研究在 a-MCI 患者的非药物干预方面具有广阔的应用前景。现就认
知训练在 a-MCI 患者临床中应用的研究进展进行综述。 |
| 关键词: 阿尔茨海默病 认知障碍 一般认知训练 计算机化认知训练 综述 |
| DOI：10.3969/j.issn.1009-6574.2022.06.013 |
|
| 基金项目: |
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| Research progress of cognitive training in patients with amnestic mild cognitive impairment |
| Huang Xiaoxu,Li Xuling |
| () |
| Abstract: |
| Alzheimer disease （AD） is a common progressive degenerative disease of central nervous
system， with progressive cognitive decline as the main clinical feature， and is the main cause of dementia.
Amnestic mild cognitive impairment （a-MCI） is a subtype of mild cognitive impairment （MCI）. Studies have
shown that most of a-MCI will progress to AD， and active intervention of a-MCI is the key to delay or reduce
the occurrence of AD. Currently， the drugs used for the treatment of amnestic MCI （a-MCI） lack large sample
evidence-based medical evidence， and clinical researchers are paying more and more attention to the research
of cognitive training in the field of non-drug treatment of a-MCI. The research of cognitive training has broad
application prospect in the non-drug intervention of patients with a-MCI. This paper reviews the research
progress of cognitive training in the clinical application of patients with a-MCI. |
| Key words: Alzheimer disease Cognition disorders General cognitive training Computerized
cognitive training Review |
